Additive manufacturing tools are capable of programmatically applying corrosion-resistant stainless steel claddings to carbon steel components (e.g., reactor pressure vessels, piping) used in nuclear reactors. Such claddings have lower dilution, a smaller heat-affected zone, and more desirable microstructures compared to arc welded claddings. This research examines the effects of proton irradiation on the corrosion performance of 309L stainless steel claddings fabricated by a laser-wire directed energy deposition additive manufacturing method. Samples are irradiated with 1.5 MeV protons to 0.5 and 1.0 displacements per atom (dpa) to simulate lifetime radiation damage of reactor pressure vessel claddings and are compared to the unirradiated case. The claddings are electrochemically tested in an aerated boric acid-containing electrolyte to simulate refueling conditions in light water reactors. All claddings are exceedingly corrosion-resistant, yet the higher radiation doses show slightly decreased performance, likely due to radiation-induced segregation effects.