The chemical process industries use a variety of equipment which sometimes requires the use of clad plates. These clad plates use carbon or low-alloy steel for the main structural or pressure-containing load bearing requirements and are clad on one side with a corrosion resistant material. These plates can be bonded through either high temperature roll bonding or by explosion cladding. After the cladding process a heat treatment is required to stress relieve the carbon or low-alloy steel and is required by either application requirements or by design code (such as ASME). Heat treating the clad plates will have an effect on the corrosion resistant clad layer and needs to also be considered. This paper will focus on the heat treat requirements of various substrate materials and how these impact nickel alloys used for the corrosion resistant clad layers. The use of standard laboratory corrosion tests to verify the corrosion resistance of the clad layer after heat treating is also reviewed here.